United States securities and exchange commission logo December 23, 2022 Willie Chiang Chairman of the Board and Chief Executive Officer PLAINS GP HOLDINGS, L.P. 333 Clay Street, Suite 1600 Houston, Texas 77002 Re: PLAINS GP HOLDINGS, L.P. Registration Statement on Form S-3 Filed December 16, 2022 File No. 333-268843 Dear Willie Chiang: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Claudia Rios, Staff Attorney, at (202) 551-8770 with any questions. Sincerely, Division of Corporation Finance Office of Energy & Transportation cc: David Oelman, Esq.